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Journal: Viruses
Article Title: Viral Epitope Scanning Reveals Correlation between Seasonal HCoVs and SARS-CoV-2 Antibody Responses among Cancer and Non-Cancer Patients
doi: 10.3390/v16030448
Figure Lengend Snippet: Comparison of quantified Ab responses. ( A ) Comparison of breadth across organisms. SARS-CoV-2 breadth was consistently higher across individuals compared to other seasonal CoVs and was not associated with age, gender, or HIV/disease status. Hierarchical clustering (McQuitty + Euclidean) ( B ) combined breadth of responses against SARS-CoV-2 and all seasonal human coronaviruses (i.e., CoV repertoire), separated into ( C ) HCoV repertoire only, and ( D ) SARS-CoV-2 breadth. Similar observations of each level can be made between cancer (n = 26) and non-cancer (n = 36) patients. Interestingly, anti-CoV/HCoV/SCoV-2 breadth is significantly higher in KS patients (n = 19) compared to in patients with other cancer types (n = 7). Abbreviations for p -values: ** p < 0.01, * p < 0.05.
Article Snippet: The phage–antibody complexes were immunoprecipitated using Protein A and Protein G magnetic beads (10008D/9D, Invitrogen, Boston, MA, USA) and a
Techniques: Comparison